The factors limiting the diagnostic accuracy of myocardial perfusion cardiac magnetic resonance imaging: coronary flow reserve and amount of myocardial scar

Background Perfusion cardiac magnetic resonance (CMR) imaging has emerged as an important clinical tool for the accurate detection of myocardial ischemia caused by significant coronary artery disease (CAD), whereas most previous studies demonstrated the diagnostic accuracy of perfusion CMR in a highly selected patient population such as those without previous myocardial infarction or lower ejection fraction (EF) etc. In the real clinical practice, however, we may encounter the patients with multiple factors affecting the accurate CMR myocardial perfusion assessment. The aim of this study was to identify the factors reducing the sensitivity of perfusion CMR for predicting significant CAD determined by the coronary angiography (CAG).